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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Venous Thrombosis I: Introduction01:30

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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The human body is a complex system of interconnected parts, and the circulatory system plays a crucial role in maintaining overall health. One key component of this system is the inferior vena cava, a large vein responsible for returning blood from the abdominopelvic viscera and abdominal walls to the heart.
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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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Splanchnic circulation refers to the network of blood vessels that supply and drain blood from the abdominal organs involved in digestion, including the stomach, liver, pancreas, intestines, and spleen. This circulation delivers essential nutrients and oxygen while removing waste products from these organs.
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Superior masenteric vein thrombosis.

C K Ho1, S T Khoo, M H Saw

  • 1Hospital Lam Wah Ee, Department of Imaging, Jalan Tan Sri Teh Ewe Lim, 11600 Pulau Pinang, Malaysia.

The Medical Journal of Malaysia
|December 12, 2013
PubMed
Summary

A young woman developed superior mesenteric vein thrombosis, linked to protein C deficiency and oral contraceptive use. Prompt anticoagulation and later surgery successfully managed her abdominal pain and intestinal obstruction.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Hematology

Background:

  • Mesenteric venous thrombosis (MVT) is a rare cause of acute abdominal pain.
  • Oral contraceptive pills are a known risk factor for hypercoagulable states.
  • Protein C deficiency is an inherited thrombophilia increasing clot risk.

Purpose of the Study:

  • To report a case of superior mesenteric vein thrombosis in a young woman.
  • To highlight the association between oral contraceptives, protein C deficiency, and MVT.
  • To describe the management and outcome of this rare condition.

Main Methods:

  • Clinical presentation and physical examination.
  • Diagnostic imaging: Ultrasound and computed tomography (CT) scan.
  • Laboratory investigations for hypercoagulable state (Protein C deficiency).

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  • Treatment: Anticoagulation, supportive therapy, and surgical intervention (bypass surgery).

    • Main Results:

    • CT scan revealed superior mesenteric vein thrombosis.
    • Protein C deficiency identified as the underlying hypercoagulable state.
    • Initial response to anticoagulation and supportive therapy.
    • Development of jejunal stricture requiring bypass surgery.
    • Successful outcome at 3-month follow-up.

    Conclusions:

    • Superior mesenteric vein thrombosis can occur in young women using oral contraceptives, especially with underlying thrombophilia like Protein C deficiency.
    • Early diagnosis and management with anticoagulation are crucial.
    • Surgical intervention may be necessary for complications such as intestinal obstruction due to stricture formation.