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Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
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Degenerative Disc Disease ll: Pathophysiology01:23

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The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
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Degenerative Disc Disease I: Introduction01:27

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Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Risk factors for first time incidence sciatica: a systematic review.

Chad E Cook1, Jeffrey Taylor, Alexis Wright

  • 1Division of Physical Therapy, Walsh University, North Canton, OH, USA.

Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy
|December 12, 2013
PubMed
Summary
This summary is machine-generated.

Identifying risk factors for first-time sciatica is crucial for prevention. Many identified risk factors, such as smoking and obesity, are modifiable and linked to unhealthy lifestyles, offering potential for primary prevention strategies.

Keywords:
low back painprimary preventionrisk factorssciatica

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Area of Science:

  • Epidemiology
  • Public Health
  • Neurology

Background:

  • Sciatica is characterized by radiating leg pain following the sciatic nerve distribution.
  • No prior studies have investigated risk factors for first-time sciatica incidence.
  • Defining first-time sciatica involves no prior history or transition from a pain-free state.

Purpose of the Study:

  • To systematically review and identify longitudinal risk factors for first-time sciatica.
  • To report incidence rates of first-time sciatica.

Main Methods:

  • Systematic review of longitudinal, observational cohort studies.
  • Included subjects of any age.
  • Eight articles met inclusion criteria from 239 identified.

Main Results:

  • Modifiable risk factors include smoking, obesity, occupational factors, and health status.
  • Non-modifiable risk factors include age, gender, and social class.
  • Incidence rates varied from <1% to 37%, influenced by definition variability.

Conclusions:

  • Many sciatica risk factors are modifiable, indicating potential for primary prevention.
  • Risk factors are associated with unhealthy lifestyles, potentially contributing to sciatica development.
  • Inconsistent definition of sciatica across studies complicates interpretation.