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Updated: May 4, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Economic analysis of an internet-based depression prevention intervention
Alexander Ruby1, Monika Marko-Holguin, Joshua Fogel
1Department of Pediatrics, General Pediatrics and Adolescent Medicine, University of Illinois at Chicago, 840 South Wood Street, M/C 856, Chicago, IL 60612, bvanvoor@uic.edu.
Developing internet-based depression prevention programs like CATCH-IT is economically viable for Accountable Care Organizations. Though safety protocols add cost, this intervention remains significantly cheaper than traditional treatments.
Area of Science:
- Digital Health Interventions
- Adolescent Mental Health
- Health Economics
Background:
- Adolescence presents a high risk for depression, yet care-seeking and treatment effectiveness are low in this demographic.
- The CATCH-IT (Competent Adolescent Coping with Health-related Troubles) program was developed as an internet-based depression prevention intervention for at-risk adolescents.
Purpose of the Study:
- To analyze the program costs of CATCH-IT, focusing on safety expenses within an Accountable Care Organization (ACO) framework.
- To evaluate the perceived value of the CATCH-IT internet program by comparing willingness-to-pay against development costs.
Main Methods:
- Cost analysis of CATCH-IT development and implementation for a 5,000-patient ACO, utilizing Medicare RBRVS data.
- Comparison of CATCH-IT costs against traditional cognitive behavioral therapy (CBT) and assessment of safety protocol cost-effectiveness.
- Evaluation of willingness-to-pay through post-study surveys to determine the program's perceived value and break-even point.
Main Results:
- Total development cost was $138,683.03 ($27.74 per patient), with implementation costs at $49,592.25 ($597.50 per patient).
- Safety costs constituted 35% of implementation costs. CATCH-IT implementation ($197.99 per participant for safety) was substantially cheaper than CBT ($1,632 per patient).
- Median willingness-to-pay was $40, with a break-even point at 3,468 individuals for development cost recovery.
Conclusions:
- Internet-based interventions like CATCH-IT are economically feasible within ACOs, offering a cost-effective alternative to current treatments.
- Despite the significant proportion of costs allocated to safety protocols, CATCH-IT demonstrates considerable cost savings compared to traditional interventions.
- Further research on the costs, outcomes, and safety of internet-based interventions is recommended for broader adoption and acceptance.
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