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Use of β-blockade and levosimendan for separation from extracorporeal life support in an infant with postoperative

Ragini Pandey1, Karthik Ramakrishnan, Alex Gooi

  • 1Department of Pediatric Cardiac Surgery, Mater Children's Hospital, Brisbane, Australia.

World Journal for Pediatric & Congenital Heart Surgery
|December 12, 2013
PubMed

Insights

Diastolic dysfunction is common in infants with left ventricular outflow tract obstruction. A management strategy using beta-blockade and levosimendan effectively treated severe postrepair diastolic dysfunction in an infant.

Area of Science:

  • Pediatric Cardiology
  • Cardiac Surgery
  • Neonatology

Background:

  • Diastolic dysfunction frequently affects infants with left ventricular (LV) outflow tract obstruction.
  • This condition can result in low cardiac output postoperatively.

Observation:

  • A case of severe postrepair diastolic dysfunction in an infant with critical congenital aortic stenosis and LV hypertrophy is presented.
  • The infant experienced significant challenges with cardiac output following surgical repair.

Findings:

  • A management strategy was implemented utilizing beta-blockade and levosimendan.
  • This therapeutic approach was effective in managing the severe diastolic dysfunction.

Implications:

  • This case highlights a potential therapeutic strategy for similar complex pediatric cardiac cases.
  • Optimizing diastolic function is crucial for improving outcomes in neonates with LV outflow tract obstruction.

Keywords:
Ross-Konno operationcardiac functionextracorporeal membrane oxygenationpharmacology

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