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Related Concept Videos

Nursing Interventions I: Taxonomy of Nursing Interventions01:03

Nursing Interventions I: Taxonomy of Nursing Interventions

Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome is...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel Disease...
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Inhibitors of Viral Protein Synthesis01:30

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...

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Updated: May 9, 2026

Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation
10:35

Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation

Published on: December 26, 2017

Immune interventions in disease.

J L Fahey, G Sarna, R P Gale

    Annals of Internal Medicine
    |February 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Recent advances in clinical immunology include new immunosuppressive drugs for autoimmune diseases and transplantation. Novel uses for interferons, interleukin-2, and monoclonal antibodies show promise in treating immunodeficiency, cancer, and in marrow transplantation.

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    In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction

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    Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation
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    Published on: December 26, 2017

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    In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
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    In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction

    Published on: January 22, 2020

    Area of Science:

    • Clinical immunology
    • Immunopharmacology
    • Immunotherapy

    Background:

    • Significant progress has been made in understanding immune regulatory systems and intercellular communication factors like cytokines.
    • Recent developments focus on three key areas: immunosuppressive drugs, interferons/interleukin-2, and monoclonal antibodies.

    Purpose of the Study:

    • To review recent advancements in clinical immunology.
    • To highlight the therapeutic potential of novel immunomodulatory agents and monoclonal antibodies.

    Main Methods:

    • Review of recent developments in immunopharmacology.
    • Analysis of clinical applications of interferons, interleukin-2, and monoclonal antibodies.
    • Examination of therapeutic strategies in autoimmune diseases, organ transplantation, immunodeficiency disorders, neoplastic diseases, and marrow transplantation.

    Main Results:

    • New and established immunosuppressive drugs offer improved treatments for autoimmune diseases and enhanced organ transplantation outcomes.
    • Interferon and interleukin-2 are being evaluated for immunodeficiency and cancer.
    • Monoclonal antibodies demonstrate therapeutic utility in marrow transplantation and antitumor therapy, building on diagnostic applications.

    Conclusions:

    • The field of clinical immunology is rapidly advancing with new therapeutic agents and strategies.
    • These advancements hold significant promise for treating a range of immune-related disorders and cancers.