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Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
3.2K
Tumor-related epilepsy and epilepsy surgery
Samden D Lhatoo1, Narges Moghimi, Stephan Schuele
1Epilepsy Center, Neurological Institute, University Hospitals Case Medical Center, Cleveland, Ohio, U.S.A.
Epilepsia
|December 17, 2013
Summary
Tumor-related epilepsy (TRE) presents diverse challenges in diagnosis and treatment. This review synthesizes current knowledge to guide clinicians managing this complex condition.
Area of Science:
- Neurology
- Neuro-oncology
Background:
- Tumor-related epilepsy (TRE) is a significant cause of seizures, characterized by considerable heterogeneity.
- Management of TRE is complex due to overlapping neurological and oncological treatment goals and limited evidence.
Purpose of the Study:
- To provide an up-to-date review of Tumor-related epilepsy (TRE).
- To address crucial aspects of TRE relevant to modern epilepsy and oncology practice.
Main Methods:
- Literature review and synthesis of current knowledge on TRE.
- Proceedings from the Sixth International Epilepsy Colloquium on Tumoral Epilepsy and Epilepsy Surgery.
Main Results:
- TRE exhibits diverse epidemiology, pathology, pathophysiology, clinical features, and outcomes.
- There is a need for comprehensive resources to guide management decisions in TRE.
Conclusions:
- Effective management of TRE requires a multidisciplinary approach integrating epilepsy and oncology expertise.
- Further research is needed to strengthen the evidence base for TRE treatment strategies.
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