Related Experiment Video

Updated: May 4, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

882

Remarkably delayed occurrence of normal surfactant composition in an extremely preterm infant

Toshihiko Nakamura1, Hiroshi Shimizu, Chiaki Nishitani

  • 1Department of Pediatrics, National Organization Hospital, Nishi-Saitama Chuo National Hospital, Tokorozawa, Japan.

Pediatrics International : Official Journal of the Japan Pediatric Society
|December 17, 2013
PubMed
Summary

Extremely preterm infants may experience delayed lung surfactant development, even after multiple artificial surfactant treatments. This case highlights prolonged respiratory distress syndrome (RDS) recovery, requiring nearly three months for normal surfactant function.

Keywords:
extremely preterm infantrespiratory distress syndromesurfactant proteins

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