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Chickenpox and stroke in children: case studies and literature review

Ana F Reis1, Patrícia Pais, José P Monteiro

  • 1Department of Paediatrics, Hospital Garcia de Orta, Almada, Portugal.

Acta Paediatrica (Oslo, Norway : 1992)
|December 17, 2013
PubMed

Insights

Postvaricella cerebral arteriopathy (PVCA) is a condition causing stroke in children after chickenpox. Early diagnosis is key, though outcomes are generally good with anti-aggregant treatment.

Area of Science:

  • Neurology
  • Pediatrics
  • Vascular Neurology

Background:

  • Postvaricella cerebral arteriopathy (PVCA) is a rare but serious complication following chickenpox infection.
  • It is characterized by stenosis of cerebral arteries leading to ischemic lesions.

Observation:

  • PVCA typically presents with acute hemiparesis and/or hemidistonia.
  • Lesions are commonly found in the internal capsule and/or basal ganglia.

Findings:

  • Anti-aggregant drugs are recommended to prevent thrombus expansion and recurrent stroke.
  • Neurologic outcomes are generally favorable irrespective of the specific therapeutic strategy employed.

Implications:

  • Chickenpox should be considered in the differential diagnosis of ischemic stroke in children.
  • Recognizing the clinical and radiological profile of PVCA aids in timely diagnosis and management.
Abstract

Keywords:
ChickenpoxIschaemic strokePostvaricella cerebral arteriopathyVaricella

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