Anesthesia and long-term outcomes after neonatal intensive care
Related Experiment Video
Updated: May 4, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
1Department of Neonatal Medicine, UCL EGA Institute for Women's Health, London, UK.
Insights
Optimizing care for extremely preterm infants focuses on reducing long-term health issues. This review examines current outcomes and anesthetic strategies, including pain management, to improve survival and quality of life for these vulnerable newborns.
Area of Science:
- Neonatalogy
- Pediatric Anesthesiology
- Perinatal Medicine
Background:
- Increasing survival rates for extremely preterm infants necessitate a focus on minimizing long-term morbidity.
- Current care strategies aim to improve neurodevelopmental and overall outcomes for these high-risk neonates.
Purpose of the Study:
- To review the current state-of-the-art outcomes for infants born at extremely low gestations.
- To identify strategies for optimizing outcomes in extremely preterm infants.
- To discuss anesthetic practices, particularly pain management, and their impact on long-term outcomes.
Main Methods:
- Literature review of current outcomes for extremely preterm infants.
- Analysis of strategies for outcome optimization.
- Discussion of anesthetic considerations and pain management in this population.
Main Results:
- Extremely preterm infants face significant risks of long-term morbidity.
- Optimizing outcomes requires a multidisciplinary approach addressing various aspects of neonatal care.
- Effective pain management during anesthesia may play a crucial role in long-term neurodevelopmental trajectories.
Conclusions:
- Care for extremely preterm infants is evolving towards minimizing long-term complications.
- Anesthetic practices, especially pain management, are critical areas for intervention to improve long-term health.
- Further research into optimizing anesthetic protocols is warranted to enhance survival and quality of life.
Abstract:
As survival is now increasing, care of the extremely preterm infant is now directed at strategies to minimize long-term morbidity. In this study, I review the current state-of-the-art outcomes for babies born at extremely low gestations and identify strategies that may be aimed at optimizing outcomes. With respect to anesthetic practice, I then go on to discuss important issues of pain management in these babies and how this may affect long-term outcomes.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Parenteral Anesthetics: Overview
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Inhalational Anesthetics: Overview
Stages of General Anesthesia

