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Updated: May 4, 2026
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Published on: August 4, 2023
Serum leptin concentrations in Mongolian women
Qimuge Suyila, Hongwei Cui, Ling Yang
1Clinical Research Center of Affiliated Hospital, Inner Mongolia Medical College, Hohhot, Inner Mongolia, China.
Objective:
The aim of our study is to elucidate the association between leptin and obesity in Mongolian women.
Method:
Total 181 women participated in the study including 118 Mongolians and 63 Han. Body mass index (BMI) was calculated by weight (kg) divided by square height (m²). Percent body fat (%fat) was detected by bioelectrical impedance analysis (BIA). Fasting serum leptin was determined by ELISA.
Result:
The average BMI and %fat of Mongolian and Han women was 25.14 ± 4.48 kg/m², 24.30 ± 3.62 kg/m² and 36.10 ± 6.23%, 33.84 ± 5.98%, respectively. Fasting serum leptin level in obese women (BMI ≥ 25) was remarkably higher than in normal weight women (18.5 < BMI < 25) in Mongolian and Han ethnic groups (all P < 0.001). Fasting serum leptin level in Mongolian women had borderline significance compared with it in Han women (P = 0.049). Multiple linear regression models revealed that ethnicity, %fat and BMI were associated with serum leptin concentrations independent of age.
Conclusion:
In Mongolian and Han women, fasting serum leptin level was positively associated with BMI and %fat (all P < 0.001).
