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[Association of epiretinal membranes with macular edema in pars planitis]
G Salcedo-Villanueva1, L Arellanes-García1, J Fromow-Guerra1
1Asociación Para Evitar la Ceguera (APEC), Hospital Dr. Luis Sánchez Bulnes, Institución de Asistencia Privada, Servicio de Retina, Coyoacán, México.
Introduction:
Pars planitis (PP) is a form of intermediate uveitis that manifests with several posterior segment complications, including cystoid macular edema (CME) and epiretinal membrane formation (ERM). On the presence of CME the patient is usually treated with anti-inflammatory and/or immunosuppressive drugs. However the presence of CME may coexist with ERM formation, and therefore the treatment could be different.
Purpose:
To determine the association between ERM and CME in PP.
Materials And Methods:
Case control series. The charts of patients diagnosed with PP were retrospectively reviewed. All patients had fluorescein angiogram (FA) and spectral domain optical coherence tomography (SD-OCT). Presence of ERM was determined by SD-OCT, while CME was determined by FA. Contingency tables were used to determine the risk of developing CME with ERM.
Results:
31 eyes presented ERM. 16 eyes presented CME. Relative risk to have CME and ERM was 0.971, with a P value of 0.77 (χ(2)).
Conclusions:
There is no association between ERM formation and the development of CME. There is no evidence to suggest a surgical approach as first line of treatment with the presence of ERM in PP.
Insights
This study found no association between epiretinal membrane (ERM) formation and cystoid macular edema (CME) in pars planitis (PP). Therefore, ERM presence does not warrant surgery as a first-line treatment for PP patients with CME.
Area of Science:
- Ophthalmology
- Immunology
- Retinal Diseases
Context:
- Pars planitis (PP) is a form of intermediate uveitis.
- Posterior segment complications include cystoid macular edema (CME) and epiretinal membrane (ERM) formation.
- Treatment for CME may differ if ERM is also present.
Purpose:
- To investigate the association between ERM and CME in patients with PP.
- To determine if ERM presence influences the development of CME.
Summary:
- A retrospective case-control study reviewed 31 eyes with ERM and 16 eyes with CME in PP patients.
- Spectral domain optical coherence tomography (SD-OCT) identified ERM, and fluorescein angiography (FA) identified CME.
- Statistical analysis revealed no significant association (Relative Risk=0.971, P=0.77).
Impact:
- Findings indicate no correlation between ERM and CME in pars planitis.
- Suggests that surgical intervention for ERM is not indicated as a primary treatment in PP patients experiencing CME.
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