Thermodilution vs pressure recording analytical method in hemodynamic stabilized patients
Abele Donati1, Andrea Carsetti1, Stefania Tondi1
1Anesthesia and Intensive Care Unit, Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, via Tronto 10/A, 60126, Ancona, Italy.
The Pressure Recording Analytical Method (PRAM) system demonstrates good agreement with pulmonary artery catheter and PiCCO for cardiac output monitoring in stable patients. This finding supports PRAM as a reliable tool for assessing cardiac output in critical care settings.
Area of Science:
- Critical Care Medicine
- Cardiovascular Physiology
- Medical Device Technology
Background:
- Cardiac output (CO) monitoring is crucial for managing critically ill patients.
- Mini-invasive devices offer alternatives to traditional methods like pulmonary artery catheters.
- The Pressure Recording Analytical Method (PRAM) is one such emerging technology.
Purpose of the Study:
- To evaluate the agreement of the PRAM system with established CO monitoring methods.
- Specifically, to compare PRAM against intermittent and continuous transpulmonary thermodilution (TP-CO) and PiCCO.
- To assess PRAM's accuracy in hemodynamically stabilized intensive care unit (ICU) patients.
Main Methods:
- Prospective clinical study conducted in mixed medical-surgical and postcardiac surgical ICUs.
- Forty-eight adult patients were enrolled.
- CO measurements were obtained using PRAM, PiCCO, and Vigilance systems.
Main Results:
- PRAM showed strong correlation with PiCCO (r=0.91) and Vigilance (r=0.83) in CO measurement.
- Percentage error for PRAM vs. PiCCO was 28%, and PRAM vs. Vigilance was 25%.
- Bias and limits of agreement indicated acceptable concordance between PRAM and reference methods.
Conclusions:
- The PRAM system exhibits good agreement with pulmonary artery catheter and PiCCO.
- PRAM is a potentially reliable method for CO monitoring in hemodynamically stabilized patients.
- Further validation in diverse patient populations may be warranted.
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