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Updated: May 4, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
Herpes Simplex epithelial keratitis associated with daily disposable contact lens wear
1Tennent Institute of Ophthalmology, Gartnavel General Hospital, United Kingdom.
Purpose:
To report a case of epithelial Herpes Simplex keratitis in a patient wearing daily disposable contact lenses.
Method:
Case report.
Results:
A 30-year-old female contact lens wearer presented to the emergency clinic with a painful, red left eye associated with an acute reduction of vision over 48 h. On examination, confluent dendritic ulcers were present on the cornea. Neither pertinent ocular nor medical history was obtained to explain such a dramatic clinical presentation.
Conclusion:
Contact lens wear was the only risk factor identified, perhaps resulting in deviation of the immune response at the ocular surface, with consequent extensive dendritic ulceration.
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