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Updated: May 4, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
Antibacterial prenylbenzoic acid derivatives from Anodendron formicinum
Xu-Jie Qin1, Paul-Keilah Lunga2, Yun-Li Zhao3
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China; University of Chinese Academy of Science, Beijing 100049, PR China.
Abstract:
A phytochemical investigation on the stems of Anodendron formicinum led to the isolation of eight prenylbenzoic acid derivatives. Three of these were new compounds, designated as formicinuosides A (1), B (2), and C (3). Their structures were elucidated on the basis of extensive spectroscopic analysis, as well as by comparison with the reported spectroscopic data. This is the first report of chemical constituents from A. formicinum and their antimicrobial activities. Among the isolated compounds, compounds 4, 6 and 8 showed significant antibacterial activities against Providensia smartii with MIC values of 0.781 μg/mL. Moreover, compound 8 showed remarkable antibacterial activity against Escherichia coli with MIC value of 0.781 μg/mL.
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