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Updated: May 4, 2026

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
An experience with paediatric burn wounds treated with a plant-derived wound therapeutic
1DM Specialist in Anesthesiology and Emergency Medicine, Santo Spirito Hospital, Rome, Italy.
Insights
This study suggests a plant-derived wound dressing, a mixture of hypericum and neem oil, effectively treats paediatric burns. The dressing demonstrated rapid healing, reduced pain, and simplicity of use in a small patient group.
Area of Science:
- Dermatology and Wound Care
- Paediatric Burn Management
- Phytotherapy in Medicine
Background:
- Evaluating novel wound care treatments for paediatric burns is crucial.
- Plant-derived compounds offer potential for effective and gentle therapeutic options.
- The study investigated a specific plant-derived wound dressing (1 Primary Wound Dressing®) composed of hypericum and neem oil.
Observation:
- A retrospective review of 9 paediatric patients with various burn types was conducted.
- The dressing was applied daily after saline cleansing, without a secondary dressing.
- Key metrics included healing time, wound size, pain levels, and complications.
Findings:
- The plant-derived dressing facilitated rapid granulation tissue induction and re-epithelialisation.
- Complete healing occurred within an average of 16.6 days.
- Patients over five years old reported significant pain reduction from 7-8/10 to 0/10 within the first week, with sustained relief.
Implications:
- 1 Primary Wound Dressing® shows promise as an effective treatment for paediatric burn wounds.
- The dressing offers benefits of pain reduction and ease of application.
- Further controlled studies with larger populations are recommended to validate these findings.
Objective:
To observe the efficacy of a plant-derived wound dressing (1 Primary Wound Dressing®), a mixture of hypericum and neem oil, in different types of paediatric burns.
Method:
A retrospective review was conducted over the complete healing course of 9 paediatric patients with a mean age of 8.17±3.35 (1-11 years), presenting mixed, partial or full-thickness burns. The treatment applied by the wound care specialist consisted of daily cleansing of the wound with a saline solution and application of 1 Primary Wound Dressing on the whole wound surface. There was no application of a secondary dressing. The time to heal, wound size, ease of handling, pain and complications were recorded. Procedural and background pain were observed in six of the patients older than 5 years (mean age 9.6±2.39, range 8-11 years). Due to the small number of patients examined during the period studied, it was not possible to perform statistical analyses.
Results:
The mean wound size was 50.76±48.32cm2 (4.63-132.0cm2). A rapid induction of granulation tissue and re-epithelialisation was observed. Time to complete healing was 16.6±4.69 days (10-22 days). No complications related to wound infection was observed. The 6 patients older than five years reported a strong relief of pain, from an initial value of 7-8 out of 10 to 0 out of 10 within the first week of treatment. This remained at the 0 out of 10 level during the second and third weeks of treatment.
Conclusion:
This retrospective, non-controlled examination suggests that 1 Primary Wound Dressing could be an effective therapy for the treatment of burn wounds, with benefits including pain reduction and simplicity of use. Further evaluations with a larger population are required to document the effectiveness of this plant-derived wound dressing in a controlled fashion.
Declaration Of Interest:
There were no external sources of funding for this study. F. Carnevali is a researcher and co-inventor of 1 Primary Wound Dressing®.
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