Related Experiment Video
Updated: May 4, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Immediate mobilization after coronary angiography or percutaneous coronary intervention following hemostasis with the
Ellen Nyholm Larsen1, Charlotte Bak Hansen2, Per Thayssen2
1Department of Cardiology, Odense University Hospital, Denmark Ellen.Nyholm.Larsen@rsyd.dk.
Insights
Immediate mobilization after cardiac procedures like coronary angiography or percutaneous coronary intervention (PCI) does not increase bleeding risk. This finding supports earlier patient mobility following femoral artery access closure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Access Management
Background:
- Standard post-coronary angiography and percutaneous coronary intervention (PCI) care involves prolonged bed rest.
- Vascular closure devices are routinely used, yet immobilization remains standard practice.
Purpose of the Study:
- To compare bleeding complications in patients undergoing cardiac catheterization with immediate mobilization versus standard bed rest.
- To evaluate safety of early mobilization after diagnostic coronary angiography (MOBS I) and after PCI (MOBS II).
Main Methods:
- Two cohorts were studied: MOBS I (diagnostic angiogram) and MOBS II (PCI).
- Patients were randomized to immediate mobilization or standard care (1-2 hours bed rest).
- Bleeding complications were categorized as major or minor, with specific definitions provided.
Main Results:
- No major bleeding complications occurred in MOBS I; minor bleeding rates were similar (2.0% vs 4.0%, p=0.41).
- In MOBS II, major bleeding rates were comparable between immediate mobilization (26.6%) and standard care (28.0%, p=0.78).
- Oozing was the predominant complication, with no significant difference between groups (22.8% vs 20.5%, p=0.62).
Conclusions:
- Immediate mobilization after coronary angiography or PCI using AngioSeal closure is safe.
- Early mobilization is not associated with an increased bleeding risk compared to standard bed rest protocols.
Background:
In patients undergoing coronary angiography or percutaneous coronary intervention (PCI), the standard post procedure regime includes immobilization and bed rest despite the use of vascular closure devices.
Aim:
In the Mobilization after Coronary Angiography or Percutaneous Coronary Intervention (MOBS) study we compared bleeding complications after cardiac catheterization with femoral artery access after mobilization immediately off the angiographic table or standard care with1 hour (MOBS I after a diagnostic angiogram) or 2 hours of bed rest before mobilization (MOBS II after PCI).
Methods:
Bleeding complications were defined as major (requiring surgery of the femoral artery, transfusion or increased hospital stay) and minor (hematoma <5 × 5 cm(2), oozing from the puncture site or minor bleeding that could be compressed manually).
Results:
In the MOBS I cohort (100 patients were mobilized immediately and 100 patients followed standard care) no major bleeding complications were seen. In the immediate mobilization group 2.0% experienced minor bleeding compared to 4.0% in the standard care group (p=0.41). In the MOBS II cohort after PCI (158 patients were mobilized immediately and 161 patients followed standard care), major bleeding complication rates did not differ significantly between the two groups: immediate mobilization group 26.6% vs. standard care group 28.0%, p=0.78. The majority of bleeding complications were due to oozing: immediate mobilization group 22.8% vs. standard care group 20.5%, p=0.62.
Conclusions:
Immediate mobilization after a coronary angiogram or PCI with the femoral access site closed by the closure device AngioSeal was not associated with increased bleeding risk compared to standard care with bed rest.
More Related Videos
Related Concept Videos
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Vascular Spasm
Acute Coronary Syndrome III: Diagnostic Studies

