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In vivo ratiometric Zn2+ imaging in zebrafish larvae using a new visible light excitable fluorescent sensor
Zhipeng Liu1, Changli Zhang, Yuncong Chen
1State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China. heweij69@nju.edu.cn zguo@nju.edu.cn.
Chemical Communications (Cambridge, England)
|December 17, 2013
Abstract:
A visible light excitable ratiometric Zn(2+) sensor was developed by integrating a Zn(2+) chelator as the ICT donor of the fluorophore sulfamoylbenzoxadiazole, which displays the Zn(2+)-induced hypsochromic emission shift (40 nm) and favors the in vivo ratiometric Zn(2+) imaging in zebrafish larvae.
