Related Experiment Video
Updated: May 4, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Treatment options for localized prostate cancer
Mira Keyes1, Juanita Crook, Gerard Morton
1Prostate Brachytherapy Program, BC Cancer Agency, 600 W 10th Ave, Vancouver, BC V5Z 4E6. mkeyes@bccancer.bc.ca.
This review outlines localized prostate cancer treatments, including surgery, radiation, brachytherapy, and active surveillance. Treatment decisions depend on cancer characteristics and patient factors.
Area of Science:
- Oncology
- Urology
Background:
- Localized prostate cancer necessitates careful treatment selection.
- Treatment options have evolved, including new standards like brachytherapy and active surveillance.
Purpose of the Study:
- To detail treatment modalities for localized prostate cancer.
- To describe patient eligibility and side effects for each option.
Main Methods:
- Review of non-randomized trials (Level II evidence) for prostate-specific antigen (PSA) outcomes.
- Inclusion of data from Canadian centers where available.
- Consideration of one randomized controlled trial (Level I evidence) comparing radical prostatectomy and brachytherapy.
Main Results:
- Treatment choice is influenced by PSA level, clinical stage, Gleason score, urinary function, comorbidities, and patient age.
- Prostate brachytherapy and active surveillance are established standard treatments.
- Overview of brachytherapy procedures, side effects, PSA outcomes, and active surveillance guidelines provided.
Conclusions:
- A multidisciplinary approach involving urology and radiation oncology is crucial.
- Family physician input is vital for patient decision-making in prostate cancer treatment.
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