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Related Experiment Video

Updated: May 4, 2026

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

The microfluidic post-array device: high throughput production of single emulsion drops.

E Amstad¹, S S Datta, D A Weitz

¹School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA. weitz@seas.harvard.edu.

|December 17, 2013

Summary

This summary is machine-generated.

This study introduces a novel microfluidic device using post arrays for high-throughput production of uniform emulsion drops. This technology offers superior size control for creating microparticles from viscous fluids.

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Last Updated: May 4, 2026

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

Glass-Based Devices to Generate Drops and Emulsions

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Published on: April 5, 2022

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Area of Science:

Microfluidics
Materials Science
Chemical Engineering

Background:

Producing monodisperse emulsion drops is crucial for microparticle fabrication.
Existing methods like membrane emulsification have limitations in size control and viscosity handling.

Purpose of the Study:

To develop a microfluidic device for high-throughput, size-controlled production of monodisperse emulsion drops.
To demonstrate the device's capability in creating polymeric microparticles from viscous solutions.

Main Methods:

A microfluidic device featuring a 2D array of regularly-spaced posts was designed.
Polydisperse crude emulsions were processed through the post array for successive droplet splitting.
High-viscosity monomer solutions were emulsified and solidified into microparticles.

Main Results:

The post-array device produced relatively monodisperse emulsion drops with controllable average size.
Droplet size distribution showed weak dependence on fluid viscosity, enabling use of highly viscous fluids.
The device achieved production rates comparable to membrane emulsification with superior size control.

Conclusions:

Post-array microfluidic devices offer precise control over emulsion drop size and polydispersity.
This technology is suitable for industrial-scale production of microparticles from challenging, high-viscosity fluids.
The device presents a promising alternative to existing emulsification techniques for advanced material manufacturing.