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Updated: May 4, 2026
Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
Published on: April 28, 2015
"Green" functionalization of magnetic nanoparticles via tea polyphenol for magnetic resonance/fluorescent
Wen Jiang1, Kuilin Lai, Kexia Liu
1National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China. zwgu@scu.edu.cn wuyao@scu.edu.cn.
Abstract:
Tea polyphenol serves as an environmentally friendly ligand-exchange molecule to synthesize multifunctional metal-doped superparamagnetic iron oxide nanoparticles via a catechol-metal coordination interaction. The resultant particles not only exhibit excellent hydrophilicity and protein adsorption resistance, but also are applicable as magnetic resonance/fluorescent dual-imaging probes due to their high T₂ relaxivity, autofluorescence and large cellular uptake.
