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Autoimmune diseases, their pharmacological treatment and the cardiovascular system

Marta Jastrzębska, Michael E Czok, Przemysław Guzik1

  • 1Department of Cardiology and Intensive Therapy, Heliodor Swiecicki University Hospital, Poznan, Poland Department of Cardiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland. pguzik@ptkardio.pl.

Cardiology Journal
|December 17, 2013
PubMed

Insights

Autoimmune diseases (AD) frequently impact the cardiovascular system, leading to serious heart conditions like heart failure and arrhythmias. Treatments for AD can also worsen cardiac health, increasing mortality and healthcare costs.

Area of Science:

  • Rheumatology
  • Cardiology
  • Immunology

Background:

  • Autoimmune diseases (AD) commonly affect the cardiovascular system.
  • Manifestations include pericarditis, myocarditis, atherosclerosis, arrhythmias, and heart failure.
  • These complications can be fatal and reduce quality of life.

Purpose of the Study:

  • To review cardiac complications associated with various autoimmune diseases.
  • To discuss the impact of AD treatments on cardiovascular health.

Main Methods:

  • Literature review of cardiovascular manifestations in AD.
  • Analysis of treatment-related cardiovascular effects.

Main Results:

  • Common cardiac issues in AD include pericarditis, myocarditis, accelerated atherosclerosis, arrhythmias, and heart failure.
  • AD treatments can negatively affect cardiovascular health, increasing mortality and healthcare expenses.

Conclusions:

  • Cardiovascular involvement is a significant and potentially fatal complication of AD.
  • Management of AD requires careful consideration of cardiac risks and treatment side effects.

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