Related Experiment Video
Updated: May 4, 2026
Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Central retinal vein occlusion in a young patient following cannabis smoke inhalation
Federico Corvi1, Giuseppe Querques, Rosangela Lattanzio
11 Department of Ophthalmology, San Raffaele Scientific Institute, Vita-Salute University, Milan - Italy.
Purpose:
To report a case of central retinal vein occlusion (CRVO) following cannabis smoke inhalation in a young patient.
Methods:
An otherwise healthy 18-year-old man without risk factors for retinal vein occlusion presented with reduced visual acuity (20/200) secondary to CRVO following cannabis smoke inhalation. Central retinal vein occlusion was diagnosed on the basis of slit-lamp fundus biomicroscopy and fluorescein angiography.
Results:
Tests for systemic causes were negative. Following one intravitreal dexamethasone implant (Ozurdex) and one ranibizumab injection (Lucentis), functional (20/20 visual acuity) and anatomic improvement was recorded. Fluorescein angiography showed a decrease in the vascular caliber and tortuosity, with no signs of retinal ischemia or edema.
Conclusions:
We report CRVO in a young adult following cannabis smoke inhalation. Its occurrence immediately after cannabis smoking further supports a link between the use of cannabis and vascular alterations.
