Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.8K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.8K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

782
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
782
Skin Cancer01:30

Skin Cancer

5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

828
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
828

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pattern of Facial Dyschromias: A Clinical and Dermoscopic Study from a Tertiary Healthcare Center in South India.

Indian dermatology online journal·2025
Same author

Clinical, Dermoscopic and Histopathological Study of Patchy Pigmentation of Lower Legs.

Indian journal of dermatology·2025
Same author

Delphi consensus on melasma management by international experts and pigmentary disorders society.

Journal of the European Academy of Dermatology and Venereology : JEADV·2025
Same author

Fatal Gastric Mucormycosis and Strongyloidiasis in a Patient with Dapsone Hypersensitivity Syndrome.

Indian dermatology online journal·2025
Same author

Trichomycosis Axillaris: A Clinicoetiological Study.

Indian dermatology online journal·2025
Same author

Balanitis Xerotica Obliterans-Related Panurethral Stricture Managed with Ayurvedic Uttar Basti therapy: A Case Report and Mini Literature Review.

Alternative therapies in health and medicine·2024
Same journal

Surgical management of acute choroidal neovascularization related submacular hemorrhage: Three case reports.

World journal of clinical cases·2026
Same journal

Ruptured primary intrahepatic ectopic pregnancy: A case report and review of literature.

World journal of clinical cases·2026
Same journal

Areas of uncertainty in endophthalmitis care.

World journal of clinical cases·2026
Same journal

Tubercular chorioretinitis mimicking sarcoidosis in a patient with celiac disease and erythema nodosum: A case report.

World journal of clinical cases·2026
Same journal

Low salivary thioredoxin-1 levels in periodontitis.

World journal of clinical cases·2026
Same journal

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal mucocele tumors: Five case reports and review of literature.

World journal of clinical cases·2026
See all related articles

Related Experiment Video

Updated: May 4, 2026

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

2.1K

Mongolian spots: How important are they?

Divya Gupta1, Devinder Mohan Thappa

  • 1Divya Gupta, Devinder Mohan Thappa, Department of Skin and STD, JIPMER, Puducherry 605006, India.

World Journal of Clinical Cases
|December 17, 2013
PubMed
Summary
This summary is machine-generated.

Mongolian spots (MS) are common birthmarks that usually fade. However, extensive or unusual MS may indicate underlying metabolic disorders or co-exist with other birthmarks, warranting medical screening.

Keywords:
Inborn errors of metabolismMongolian spot

More Related Videos

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
15:57

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle

Published on: July 11, 2015

13.8K
Enzyme-linked Immunospot Assay ELISPOT: Quantification of Th-1 Cellular Immune Responses Against Microbial Antigens
06:13

Enzyme-linked Immunospot Assay ELISPOT: Quantification of Th-1 Cellular Immune Responses Against Microbial Antigens

Published on: November 23, 2010

34.3K

Related Experiment Videos

Last Updated: May 4, 2026

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

2.1K
Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
15:57

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle

Published on: July 11, 2015

13.8K
Enzyme-linked Immunospot Assay ELISPOT: Quantification of Th-1 Cellular Immune Responses Against Microbial Antigens
06:13

Enzyme-linked Immunospot Assay ELISPOT: Quantification of Th-1 Cellular Immune Responses Against Microbial Antigens

Published on: November 23, 2010

34.3K

Area of Science:

  • Dermatology
  • Genetics
  • Pediatrics

Background:

  • Mongolian spots (MS) are common congenital, macular, blue-gray pigmented lesions, typically found on the lumbosacral area.
  • While usually benign and self-resolving by early childhood, atypical presentations like widespread, extrasacral, or persistent MS can occur.
  • These aberrant Mongolian spots may be misdiagnosed as child abuse or confused with other dermal melanocytoses.

Purpose of the Study:

  • To review the significant associations of Mongolian spots.
  • To highlight the importance of screening newborns with extensive Mongolian spots.

Main Methods:

  • Literature review focusing on Mongolian spots and their associated conditions.
  • Analysis of clinical presentations and diagnostic implications of aberrant Mongolian spots.

Main Results:

  • Mongolian spots can persist into adulthood and appear in extrasacral locations.
  • Atypical Mongolian spots are associated with inborn errors of metabolism (e.g., GM1 gangliosidosis, mucopolysaccharidoses) and vascular birthmarks (phakomatosis pigmentovascularis).
  • Early documentation of Mongolian spots at birth is crucial to rule out abuse and identify potential underlying conditions.

Conclusions:

  • Extensive or atypical Mongolian spots necessitate further investigation for associated metabolic disorders and other birthmarks.
  • Screening infants with widespread Mongolian spots is vital for early diagnosis and management of potential health issues.
  • Recognizing the diverse clinical spectrum of Mongolian spots improves patient outcomes and diagnostic accuracy.