[The system of assessment of the severity of ultrasound epilepsy in rats]
Patologicheskaia Fiziologiia I Eksperimental'Naia Terapiia
|December 18, 2013
Abstract:
The method of induction of epileptic reactions in rats by ultrasound (24.3 kHz; 116dB) and the system of severity estimation of epileptic reaction was developed. Ultrasound--frequency above 20 kHz--absolutely silent for a person, may cause epileptic reaction in 3-9% of the rats. The possibility of using ultrasound--induced epilepsy in rats to evaluate anticonvulsant activity of drugs it is shown.
