Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

35.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
35.5K
Next-generation Sequencing03:00

Next-generation Sequencing

87.9K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
87.9K
Human Genetics01:28

Human Genetics

2.0K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
2.0K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

2.5K
2.5K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

7.5K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
7.5K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multicytokine-based transcriptome-wide association study for 7 inflammatory skin disorders identifies candidate causal genes in keratinocytes.

The Journal of allergy and clinical immunology·2026
Same author

Dissecting the Causal Links Between Acne Vulgaris and Cardiometabolic Health Using Mendelian Randomization.

The Journal of investigative dermatology·2026
Same author

Genetic proxies of GLP1R expression are associated with lower risk of psoriasis and psoriatic arthritis.

The British journal of dermatology·2026
Same author

Exome sequencing and analysis of 44,028 British South Asians enriched for high autozygosity.

Nature genetics·2026
Same author

Genome-wide meta-analysis in lichen sclerosus identifies 14 genomic risk loci.

The British journal of dermatology·2026
Same author

Genetic exploration of the relationship between liability to psychiatric disorders and acne vulgaris.

European journal of human genetics : EJHG·2026

Related Experiment Video

Updated: May 4, 2026

Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

6.1K

The future of genomics for developmentalists.

Robert Plomin1, Michael A Simpson1

  • 1King's College London.

Development and Psychopathology
|December 18, 2013
PubMed
Summary

Genomic science advances, including whole-genome sequencing, will enhance understanding of behavioral development. Polygenic scores will help predict children's genetic risk and resilience, improving research and clinical applications.

Area of Science:

  • Genomic science
  • Behavioral development
  • Quantitative genetics

Background:

  • Genomic science is merging with quantitative genetics to identify genes influencing complex traits.
  • Current methods face challenges like the 'missing heritability' problem.
  • Whole-genome sequencing promises to identify all DNA variations, including rare ones.

Purpose of the Study:

  • To explore the implications of genomic advances for understanding behavioral development.
  • To highlight the role of quantitative and molecular genetics in future research.
  • To discuss the application of polygenic scores in developmental science.

Main Methods:

  • The paper discusses the integration of quantitative and molecular genomics.
  • It highlights the potential of whole-genome sequencing.

More Related Videos

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.2K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

36.1K

Related Experiment Videos

Last Updated: May 4, 2026

Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

6.1K
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.2K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

36.1K
  • It introduces the concept and application of polygenic scores.

    • Main Results:

    • Whole-genome sequencing will improve the identification of genetic variants contributing to complex traits.
    • Polygenic scores, composed of numerous DNA variants, will be crucial for predicting genetic risk and resilience in children.
    • Widespread availability of whole-genome sequences will streamline genomic data acquisition for research and clinical use.

    Conclusions:

    • Genomic science is poised to significantly advance the study of behavioral development.
    • Polygenic scores and whole-genome sequencing represent key future tools for developmentalists.
    • These genomic advancements will facilitate personalized risk and resilience assessments in children.