Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of ecological momentary assessment via wearable devices for detecting acute suicide risk in psychiatric inpatients.

Frontiers in psychiatry·2026
Same author

Spatiotemporal Reconfiguration of Functional Brain Networks Following Transcranial Focused Ultrasound Stimulation.

Neuromodulation : journal of the International Neuromodulation Society·2026
Same author

Auricular Ultrasonic Vagus Nerve Stimulation: Effectiveness of Blinding and the Occurrence of Adverse Effects in People with Tinnitus.

Brain sciences·2026
Same author

Resting-state functional connectome correlates of suicide attempt history and childhood trauma in major depressive disorder.

Journal of affective disorders·2026
Same author

Transcutaneous Auricular Vagus Nerve Stimulation Enhances Emotional Bias Toward Happiness in Healthy Young Adults: A Comparative Study of Electric and Ultrasound Stimulation.

Neuromodulation : journal of the International Neuromodulation Society·2026
Same author

Acceptability of cannabidiol as a treatment for people at clinical high risk for psychosis.

Frontiers in psychiatry·2026

Related Experiment Video

Updated: May 4, 2026

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
13:26

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

11.3K

Preferential detachment during human brain development: age- and sex-specific structural connectivity in diffusion

Sol Lim1, Cheol E Han2, Peter J Uhlhaas3

  • 1Department of Brain & Cognitive Sciences, Seoul National University, Seoul 151-747, South Korea School of Computing Science and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

Cerebral Cortex (New York, N.Y. : 1991)
|December 18, 2013
PubMed
Summary

Human brain maturation shows stable network organization despite streamline loss. This loss primarily impacts specific fiber tracts, with females experiencing it earlier than males.

Keywords:
brain connectivityconnectomematurationnetwork analysistractography

More Related Videos

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

27.9K
Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

24.5K

Related Experiment Videos

Last Updated: May 4, 2026

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
13:26

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

11.3K
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

27.9K
Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

24.5K

Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Brain Connectivity

Background:

  • Human brain maturation involves prolonged development of large-scale networks extending into adulthood.
  • Understanding which structural and functional brain properties change or remain stable over time is crucial.

Purpose of the Study:

  • To investigate changes in structural brain connectivity from childhood to adulthood.
  • To identify which network properties, such as small-world parameters and modularity, are stable during maturation.

Main Methods:

  • Diffusion tensor imaging (DTI) was used to analyze structural connectivity in 121 participants aged 4–40.
  • Analysis focused on small-world parameters, modularity, and the number of fiber tracts (streamlines).

Main Results:

  • The number of fiber tracts, small-world topology, and modular organization remained largely stable with age.
  • A decrease in streamlines primarily affected short, within-module, and within-hemisphere connections.
  • Streamline loss occurred earlier in females than in males.

Conclusions:

  • Core properties of structural brain connectivity, like small-world and modular organization, are maintained during maturation.
  • Streamline loss is a targeted process, affecting specific types of fiber tracts.
  • Sex differences exist in the timing of streamline loss during brain development.