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Two new compounds from the fungus Penicilliumcrustosum YN-HT-15
Yan-Ping Liu1, Gang Chen, Hai-Feng Wang
1a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang , 110016 , China.
Abstract:
Our current natural product program researches the second metabolites of a fungus Penicilliumcrustosum YN-HT-15 isolated from the red soil (Yunnan Province, China), to discover potential antitumor chemical entities. Two new compounds were isolated from the ethyl acetate extract of the fermentation broth of the fungus, and their structures were characterized as 1-(2',4'-dihydroxy-5'-methyl-3'-methylsulfanylmethyl-phenyl)-ethanone and R-3-(3'-acetyl-2',6'-dihydroxy-5'-methylphenyl)-2-methyl-propionic acid methyl ester on the basis of spectroscopic data.
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