Pulmonary arterial hypertension in HIV infection: a concise review
Hai-Long Dai1, Ming Zhang2, Zhi-Cheng Xiao3
1Department of Cardiology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, PR China; The Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming, PR China; Department of Anatomy and Developmental Biology, Monash University, Clayton, Australia.
Abstract:
Pulmonary arterial hypertension (PAH) is an infrequent but nevertheless serious life threatening severe complication of human immunodeficiency virus (HIV) infection. In today's era of antiretroviral therapy (ART), the mortality of HIV patients has greatly reduced due to improved immune function and fewer opportunistic infections. However, these patients have an increased incidence of PAH. In this review, we will mainly discuss HIV-related pulmonary arterial hypertension (HRPH) in terms of the epidemiology, pathogenesis, clinical characteristics and treatment.
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