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Unexplained chronic leukopenia treated with oral iron supplements
Ayman Abuirmeileh1, Anas Bahnassi, Amjad Abuirmeileh
1Internal Medicine, Isawiya Medical Center, Amman, Jordan.
International Journal of Clinical Pharmacy
|December 19, 2013
Summary
Iron deficiency anemia can cause chronic neutropenia (low white blood cell count). Treating iron deficiency corrected this patient's unexplained neutropenia, suggesting a new link.
Area of Science:
- Hematology
- Internal Medicine
Background:
- Chronic idiopathic neutropenia is a diagnosis of exclusion.
- Iron deficiency anemia is common and can have various causes.
Observation:
- A patient with a 16-year history of unexplained chronic neutropenia and iron deficiency anemia was treated for iron deficiency.
- Treatment involved two and a half months of supervised iron supplementation during hospitalization.
Findings:
- Correction of iron deficiency anemia led to the resolution of chronic neutropenia.
- This suggests a potential causal link between iron deficiency and neutropenia.
Implications:
- Unexplained chronic neutropenia may, in some cases, be a manifestation of iron deficiency.
- Further research is warranted to identify and characterize iron deficiency-induced neutropenia.
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