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Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

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Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
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Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

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Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
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Related Experiment Video

Updated: May 4, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

23.9K

Agminate lichen aureus.

Violeta Duarte Tortelly1, Roberto Souto da Silva1, Amanda Nascimento Cavalleiro de Macedo Mota1

  • 1University of the State of Rio de Janeiro, Pedro Ernesto University Hospital, Rio de JaneiroRJ, Brazil.

Anais Brasileiros De Dermatologia
|December 19, 2013
PubMed
Summary
This summary is machine-generated.

Lichen aureus, a rare pigmented purpura variant, typically presents as asymptomatic brownish lesions on the lower limbs. This case highlights a confluent agminate pattern, aiding in diagnosis.

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Last Updated: May 4, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

23.9K

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Lichen aureus is a rare, chronic, benign variant of pigmented purpura.
  • It commonly affects the lower extremities, presenting as coppery or golden macules and papules.

Observation:

  • This report details a specific case of lichen aureus.
  • The case exhibited a confluent morphological pattern, termed agminate lichen aureus.

Findings:

  • Diagnosis of lichen aureus relies on clinical and histopathological examination.
  • Dermatoscopy is a valuable adjunct for presumptive diagnosis.

Implications:

  • Recognizing the agminate pattern of lichen aureus can aid in clinical diagnosis.
  • Further research into dermatoscopic patterns may improve diagnostic accuracy for rare skin conditions.