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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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Pyoderma gangrenosum in a newborn--case report.

Francisca Regina Oliveira Carneiro1, Maria Amélia Lopes dos Santos2, Brena Andrade de Sousa3

  • 1São Paulo Federal University.

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Summary

Pyoderma gangrenosum, a rare inflammatory skin condition, can affect newborns. This case shows a newborn with ulcers responded quickly to oral prednisone treatment.

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Area of Science:

  • Dermatology
  • Pediatric Dermatology
  • Neonatology

Background:

  • Pyoderma gangrenosum is a rare, chronic, inflammatory skin disease of unknown cause.
  • It typically presents as painful, necrotizing, noninfectious ulcers, primarily affecting adults aged 25-54.
  • Pediatric cases are rare (less than 4%), often involving the head, face, buttocks, and genital areas.

Observation:

  • A case report of a newborn presenting with hemorrhagic and necrotic ulcers is described.
  • The ulcers were distributed across the abdomen, buttocks, and genital region.
  • This presentation is unusual for pyoderma gangrenosum in neonates.

Findings:

  • The newborn exhibited symptoms consistent with pyoderma gangrenosum.
  • The condition showed a rapid and effective response to treatment with oral prednisone.
  • This suggests early intervention with corticosteroids can be beneficial in neonatal cases.

Implications:

  • This case highlights the possibility of pyoderma gangrenosum in newborns presenting with specific ulcer patterns.
  • It underscores the efficacy of systemic corticosteroids, specifically oral prednisone, in treating neonatal pyoderma gangrenosum.
  • Further research into the etiology and management of pyoderma gangrenosum in infants is warranted.