Forme Fruste Keratoconus Imaging and Validation via Novel Multi-Spot Reflection Topography

Area of Science:

• Ophthalmology
• Corneal Imaging
• Refractive Surgery

Background:

• Evaluating novel anterior surface imaging for forme fruste keratoconus (FFKC).
• Assessing a multi-spot, multicolor light-emitting-diode (LED) tear film-reflection imaging technology.
• Investigating the safety, efficacy, and applicability of this new technology.

Observation:

• A 45-year-old male with asymmetric FFKC underwent multicolor-spot reflection topography.
• Elevation and sagittal curvature maps were compared with Placido topography and Scheimpflug imaging.
• Keratometry measurements showed good agreement across all three imaging systems.

Findings:

• The multicolor spot-reflection topographer demonstrated comparable results to Placido and Scheimpflug systems.
• Average repeatability of keratometry measurements was ±0.35 D for the multicolor device.
• Excellent agreement was observed between the instruments on elevation and curvature maps.

Implications:

• The ease of use and comparable results suggest wider clinical application for the multicolor spot-reflection topographer.
• Potential for screening young adults for early keratoconus.
• Broadened application for identifying potential candidates for laser corneal refractive surgery.