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Published on: July 8, 2025
Multicystic dysplastic kidney complicated by pyelonephritis.
Chad J Cooper1, Sarmad Said1, Sayeed Khalillullah1
1Department of Internal Medicine, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, U.S.A.
This case report details a rare instance of pyelonephritis in a patient with multicystic dysplastic kidney (MCDK). The 21-year-old female presented with symptoms of a kidney infection, highlighting the unusual complication of pyelonephritis in MCDK.
Area of Science:
- Nephrology
- Urology
- Medical Case Reports
Background:
- Multicystic dysplastic kidney (MCDK) is a congenital condition affecting 1 in 4300 live births, characterized by non-functional kidneys with multiple cysts.
- MCDK typically presents unilaterally, most often in the left kidney, and is defined by the absence of normal renal parenchyma.
Purpose of the Study:
- To report a rare case of pyelonephritis complicating multicystic dysplastic kidney (MCDK).
- To highlight the unusual occurrence of infection in a non-functional dysplastic kidney.
Main Methods:
- A case study of a 21-year-old female with a history of MCDK.
- Clinical presentation including flank pain, dysuria, and fever.
- Diagnostic workup involving urinalysis, urine culture, and CT scan of the abdomen and pelvis.
Main Results:
- The patient presented with symptoms indicative of a urinary tract infection, with urinalysis and urine culture confirming Escherichia coli infection.
- CT scan revealed findings consistent with MCDK in the left kidney and perinephric stranding, suggesting inflammation.
- The patient was treated with Levofloxacin.
Conclusions:
- Infections involving the MCDK itself, such as pyelonephritis, are exceptionally rare in medical literature.
- This case underscores the possibility of pyelonephritis in patients with MCDK, despite its rarity.
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