Related Experiment Video
Updated: May 4, 2026

Experimental and Data Analysis Workflow for Soft Matter Nanoindentation
Published on: January 18, 2022
Local and systemic effects of mechanico-chemical retraction
Mark Donaldson1, Jason H Goodchild2
1Director of Pharmacy Services, Kalispell Regional Medical Center, Kalispell, Montana; Clinical Professor, University of Montana, Skaggs School of Pharmacy, Missoula, Montana; Clinical Associate Professor, Oregon Health and Science University, School of Dentistry, Portland, Oregon.
Abstract:
The process of recording an acceptable fixed prosthodontic impression must include appropriate tissue management. This article reviews the effects of mechanical and chemical tissue retraction for fixed prosthodontics, specifically discussing the use of retraction cord with or without chemicals to control sulcular hemorrhage and moisture. Common astringents, hemostatics, and vasoconstrictors used in dentistry as gingival retraction agents are discussed, and recommendations for modification of patient and treatment management are provided.
Related Concept Videos
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Cell-matrix's Response to Mechanical Forces
Anchoring junctions mechanically attach a cell to the...
Local Anesthetics: Pharmacokinetics
Acute Inflammation II: Local and Systemic Effects
Effects of Chemicals: Overview

