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A functional polymorphism in ADAR1 gene affects HBsAg seroclearance both spontaneously and interferon induced

Xiaopan Wu1, Weimei Shi, Jia Wu

  • 1National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.

Liver International : Official Journal of the International Association for the Study of the Liver
|December 20, 2013
PubMed
Summary

The rs4845384 polymorphism in the ADAR1 gene is linked to Hepatitis B surface antigen (HBsAg) seroclearance. This genetic variation influences ADAR1 expression, impacting HBsAg clearance in chronic hepatitis B patients.

Keywords:
HBsAg seroclearanceInterferonluciferase assaysnatural clearanceqPCR

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