Relationship between poor decision-making process and fatigue perception in Parkinson's disease patients
Naia Sáez-Francàs1, Jorge Hernández-Vara2, Margarita Corominas-Roso1
1Servei de Psiquiatria, Hospital Universitari Vall d'Hebron, CIBERSAM, Department of Psychiatry, Universitat Autònoma de Barcelona, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
Journal of the Neurological Sciences
|December 20, 2013
Summary
Fatigued Parkinson's disease patients exhibit impaired decision-making, potentially due to abnormal somatic symptom interpretation. This finding highlights a crucial non-motor symptom impacting daily functioning in Parkinson's disease (PD).
Area of Science:
- Neuroscience
- Clinical Psychology
- Movement Disorders
Background:
- Fatigue is a prevalent non-motor symptom in Parkinson's disease (PD).
- The underlying mechanisms of perceived fatigue in PD are not fully understood.
- Somatic symptom misinterpretation may contribute to fatigue and affect decision-making.
Purpose of the Study:
- To investigate the relationship between fatigue and decision-making abilities in Parkinson's disease patients.
- To test the hypothesis that fatigued PD patients perform worse on decision-making tasks.
Main Methods:
- 89 Parkinson's disease patients were assessed for fatigue using the Parkinson Fatigue Scale.
- Psychopathology and neuropsychological tests, including the Iowa Gambling Task, were administered.
- Fatigue status was determined based on established criteria.
Main Results:
- 37.1% of patients met the criteria for fatigue.
- Fatigued patients reported higher levels of anxiety, impulsivity, and depression.
- Fatigued PD patients demonstrated significantly poorer performance on the Iowa Gambling Task, indicating impaired decision-making.
Conclusions:
- Fatigue in Parkinson's disease is associated with abnormal decision-making processes.
- This impairment may stem from altered processing of somatic markers.
- Findings suggest fatigue impacts effortful decision-making in PD.
Keywords:
Decision-makingFatigueIowa Gambling TaskParkinson's diseasePrefrontal cortexPsychopathologyMore Related Videos
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