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Related Experiment Video

Updated: May 4, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
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Iodine status in pregnancy.

N S Dodd1, J Madan

  • 1Department of Foods Science and Nutrition, SVT College of Home Science, SNDT Women's University, Bombay - 400 049, India.

Asia Pacific Journal of Clinical Nutrition
|December 20, 2013
PubMed
Summary
This summary is machine-generated.

Pregnant women in urban slums show high goitre rates and mild iodine deficiency, impacting thyroid function. This highlights the need for improved iodine status monitoring and interventions during pregnancy.

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Area of Science:

  • Endocrinology
  • Public Health
  • Nutritional Science

Background:

  • Iodine deficiency during pregnancy poses risks to maternal and fetal health.
  • Assessing iodine status is crucial for preventing thyroid dysfunction in vulnerable populations.
  • Urban slum dwellers often face nutritional challenges impacting micronutrient intake.

Purpose of the Study:

  • To evaluate the iodine status and thyroid function in pregnant women from urban slums in Bombay.
  • To determine the prevalence of goitre and assess biochemical indicators of iodine deficiency.
  • To investigate the relationship between iodine status, goitre, and thyroid hormone levels.

Main Methods:

  • Clinical examination for goitre assessment (total goitre rate and visible goitre rate).
  • Biochemical analysis of urinary iodine excretion to assess iodine intake.
  • Measurement of thyroid hormones (T3, T4) and thyroid-stimulating hormone (TSH) levels.

Main Results:

  • A high total goitre rate (45%) and visible goitre rate (3.04%) were observed, increasing during pregnancy.
  • Mild iodine deficiency was indicated by low urinary iodine excretion in 55% of women.
  • Elevated T3 (64%) and T4 (40%) levels were noted, with normal TSH in most, suggesting potential thyroid hormone resistance or adaptation.

Conclusions:

  • Pregnant women in Bombay's urban slums exhibit significant iodine deficiency and goitre prevalence.
  • The findings underscore the public health importance of iodine supplementation and monitoring in this demographic.
  • Further research is needed to understand the implications of altered thyroid hormone levels in the context of iodine deficiency.