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Revisiting pneumonia and exposure status in infants born to HIV-infected mothers
Rasa Izadnegahdar1, Matthew P Fox, Prakash Jeena
1From the *Center for Global Health and Development, Boston University; †Department of Epidemiology, Boston University School of Public Health, Boston, MA; ‡Pediatrics Department, N. Mandela School of Medicine, University of Kwazulu-Natal, Durban, South Africa; §Department of Maternal Newborn Child and Adolescent Health, World Health Organization, Geneva, Switzerland; and ¶Department of International Health, Boston University School of Public Health, Boston, MA.
Abstract:
HIV-exposed uninfected infants are an increasing population. Past analyses have often categorized these infants as uninfected leading to inaccurate conclusions. We present a HIV exposure, rather than infection, based reanalysis of treatment failure among children with pneumonia to show that failure odds among HIV-exposed uninfected infants are intermediate between their unexposed and infected counterparts. Additional prospective studies aimed at better understanding this population are needed.
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