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Updated: May 4, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
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An important side reaction using the thiol, 3,6-dioxa-1,8-octanedithiol (DODT), in 9-fluorenylmethoxycarbonyl-based

Paul W R Harris1, Renata Kowalczyk, Sung-Hyun Yang

  • 1School of Chemical Sciences, The University of Auckland, 23 Symonds St, Auckland, 1142, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.

Journal of Peptide Science : an Official Publication of the European Peptide Society
|December 20, 2013
PubMed

Keywords:
3,6-dioxa-1,8-ocatanedithiolalkylationmethioninepeptide cleavage

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