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Platelet receptors; an instrumental of platelet physiology

Muhammad Saboor1, Qamar Ayub2, Samina Ilyas3

  • 1Muhammad Saboor, Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan.

Pakistan Journal of Medical Sciences
|December 20, 2013
PubMed

Platelets play an important role in hemostasis, inflammation, host defense, tumor growth and metastasis. Platelets receptors are instrumental in platelet-platelet aggregation and interaction of platelets with leukocytes, endothelial cells and coagulation factors. These receptors are also the targets for antiplatelet drugs. This review focuses on the role of platelet receptors in human physiology. Data were extracted from peer-reviewed journals using MEDLINE and EMBASE databases, and the following terms (platelets, platelet receptors, CD markers, integrins, tetraspanins, transmembrane receptors, prostaglandin receptors, immunoglobulin superfamily receptors) were used.

Keywords:
IntegrinsPlatelet receptorsSelectinsTetraspanins

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