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Updated: May 4, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Two new flavanonols from the bark of Akschindlium godefroyanum
Nattapong Chaipukdee1, Somdej Kanokmedhakul, Ratsami Lekphrom
1a Faculty of Science, Khon Kaen University , Khon Kaen 40002 , Thailand.
Abstract:
The first phytochemical investigation of the bark of Akschindlium godefroyanum (Kuntze) H. Ohashi (Fabaceae), a Thai herbal medicine, resulted in the isolation of two new flavanonols, 7,3',5'-trihydroxy-5-methoxyflavanonol (1) and 7,4'-dihydroxy-5,3'-dimethoxyflavanonol (2), and eight known compounds comprising one flavonol, geraldol (3); three flavanonols, (+)-taxifolin (4), (+)-fustin (5) and aromadendrin 5-methyl ether (6); one catechin, (-)-epigallocatechin (7); one triterpenoid, lupeol (8); one steroid, stigmasterol (9) and one steroid glycoside, stigmasterol-3-O-β-d-glucoside (10). Their structures were identified by spectroscopic methods.

