Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

3.0K
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
3.0K
Transdermal Drug Delivery Systems01:18

Transdermal Drug Delivery Systems

233
Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...
233
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

77
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
77

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of the half-life of <sup>214</sup>Po, including long-term studies to investigate potential seasonal effects.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2026
Same author

177Lu-based radioligand therapy: A retrospective multicenter analysis to calculate the effective half-life and follow-up dose for the public.

Nuklearmedizin. Nuclear medicine·2026
Same author

Determination of the <sup>107</sup>Pd half-life.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

The revised German guideline on the monitoring for intakes of radionuclides.

Radiation and environmental biophysics·2025
Same author

First intercomparison of <sup>241</sup>Am activity measurements using primary methods including magnetic micro-calorimetrers.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

Study of a method to correct for accidental coincidences in TDCR measurements.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025

Related Experiment Video

Updated: May 4, 2026

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
09:51

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

Published on: September 19, 2025

651

A portable TDCR system.

Ole Nähle1, Qi Zhao1, Carsten Wanke2

  • 1Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany.

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|December 21, 2013
PubMed
Summary
This summary is machine-generated.

A new portable triple-to-double-coincidence ratio (TDCR) system enables accurate radioactivity standardization outside labs. This miniature TDCR system, developed for the MetroFission project, shows promising results for field measurements.

Keywords:
Activity standardizationCoincidence and dead-time logicEMRPFree parameter modelPortable TDCRTDCR

More Related Videos

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

7.9K
Droplet Digital TRAP ddTRAP: Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction
06:38

Droplet Digital TRAP ddTRAP: Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction

Published on: May 3, 2019

8.2K

Related Experiment Videos

Last Updated: May 4, 2026

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
09:51

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

Published on: September 19, 2025

651
A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

7.9K
Droplet Digital TRAP ddTRAP: Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction
06:38

Droplet Digital TRAP ddTRAP: Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction

Published on: May 3, 2019

8.2K

Area of Science:

  • Metrology
  • Nuclear Instrumentation

Background:

  • The triple-to-double-coincidence ratio (TDCR) method is crucial for radioactivity standardization in metrology.
  • There's a growing need for accurate, portable systems for activity determination outside traditional laboratories.

Purpose of the Study:

  • To develop and evaluate a miniature, portable TDCR system for accurate radioactivity measurements.
  • To assess the performance of the portable system against a well-established reference TDCR system.

Main Methods:

  • Development of a portable TDCR system utilizing channel photomultipliers, a separate electronics bin, and computer-based data acquisition.
  • Extensive testing and comparison of the miniature TDCR system with the PTB's reference TDCR system.

Main Results:

  • The portable TDCR system, developed under the EMRP "MetroFission" project, was successfully tested.
  • Performance evaluation involved direct comparison with the highly characterized PTB reference TDCR system.

Conclusions:

  • The miniature TDCR system demonstrates potential for accurate activity determination in field applications.
  • The developed portable system offers a viable solution for radioactivity standardization beyond specialized laboratory settings.