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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

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Probiotics for future caries control: a short-term clinical study.

Anitha Chinnappa, Harish Konde, Sapna Konde¹

¹Department of Pedodontics & Preventive Dentistry, AECS Maaruthi College of Dental Sciences and Research Centre, Bangalore, Karnataka, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research

|December 21, 2013

Summary

Probiotic ice cream and curds significantly reduced salivary mutans streptococci (MS) in children after seven days. These probiotic foods offer a promising strategy for preventing enamel demineralization.

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Area of Science:

Oral microbiology
Probiotics
Dental caries prevention

Background:

Mutans streptococci (MS) are key pathogens in dental caries development.
Probiotics show potential in modulating oral microbiota.
Dietary interventions are explored for caries prevention.

Purpose of the Study:

To compare the effect of probiotic ice cream and probiotic curds on salivary mutans streptococci levels.
To evaluate changes in MS counts before and after consumption over a 7-day period.

Main Methods:

Forty caries-free children (12-14 years) were divided into four groups.
Groups received either probiotic or plain ice cream/curd for 7 days.
Saliva samples were analyzed at baseline, 1 hour, and 7 days post-consumption.

Main Results:

A reduction in salivary MS was observed 1 hour after consumption in all groups.
Probiotic ice cream and curds demonstrated a statistically significant reduction in MS counts after 7 days compared to controls (P < 0.001).
No significant difference was found between probiotic ice cream and probiotic curd in MS reduction.

Conclusions:

Probiotic products can displace pathogenic oral bacteria.
Probiotic ice cream and curds represent an alternative strategy for preventing enamel demineralization.
Further research can explore the long-term efficacy and specific strains for oral health.