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Complete Genome of Salmonella enterica Serovar Typhimurium Myophage Maynard

Casey O Tatsch1, Thammajun L Wood, Karthik R Chamakura

  • 1Center for Phage Technology, Texas A&M University, College Station, Texas, USA.

Genome Announcements
|December 21, 2013
PubMed

Insights

Researchers sequenced the genome of the Maynard phage, which infects Salmonella Typhimurium. This phage may offer a potential therapeutic strategy against this foodborne pathogen.

Area of Science:

  • Microbiology
  • Genomics
  • Bacteriophage research

Background:

  • Salmonella enterica serovar Typhimurium is a significant food safety concern.
  • Bacteriophages (phages) are viruses that infect bacteria and are being explored as potential antimicrobials.

Purpose of the Study:

  • To sequence and characterize the complete genome of the S. Typhimurium T4-like myophage Maynard.
  • To provide a genomic resource for understanding phage-host interactions and developing phage-based therapies.

Main Methods:

  • Whole-genome sequencing of phage Maynard.
  • Bioinformatic analysis of the phage genome to identify genes and features.

Main Results:

  • The complete genome sequence of phage Maynard was determined.
  • Key genomic features and potential functional genes of the T4-like myophage were described.

Conclusions:

  • The genomic data of phage Maynard provides a foundation for further research into its therapeutic potential against Salmonella Typhimurium.
  • Understanding phage genomes is crucial for developing novel strategies to combat bacterial infections.

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