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Updated: May 4, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
A new bis-labdanic diterpene from the rhizomes of Alpinia pahangensis
Yasodha Sivasothy1, Halijah Ibrahim2, Audra Shaleena Paliany2
1Department of Chemistry, Faculty of Science, University Malaya, Kuala Lumpur, Malaysia.
Abstract:
The rhizomes of Alpinia pahangensis yielded a new bis-labdanic diterpene for which the name pahangensin C (1) was proposed along with twelve known analogues (2-13). The structure of 1 was elucidated via spectroscopic methods including 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Compounds 2 and 12 were isolated for the first time from the genus Alpinia. This is the second occurrence of compounds 2 and 12 in the Zingiberaceae family. Selected analogues exhibited moderate to strong inhibitory activity against Staphylococcus aureus and Bacillus cereus.
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