T2 FLAIR artifacts at 3-T brain magnetic resonance imaging
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Updated: May 4, 2026

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
Published on: June 5, 2017
Eleftherios Lavdas1, Ioannis Tsougos2, Stella Kogia3
1Technological Educational Institute of Athens, Radiology Department, Athens, Greece.
Abstract:
The purpose of this retrospective clinical study was to identify and evaluate the presence and frequency of T2 FLAIR artifacts on brain MRI studies performed at 3 T. We reviewed axial T2 FLAIR images in 200 consecutive unremarkable brain MRI studies performed at 3 T. All studies were reviewed for the presence of artifacts caused by pulsatile CSF flow, magnetic susceptibility and no nulling of the CSF signal. T2 FLAIR images introduce several artifacts that may degrade image quality and mimic pathology. Knowledge of these artifacts and increased severity and frequency at 3 T is of particular importance in avoiding a misdiagnosis.
Insights
This study examined T2 FLAIR artifacts on 3 Tesla brain MRIs. Researchers found these artifacts, caused by CSF flow and magnetic susceptibility, are frequent and can mimic pathology, potentially leading to misdiagnosis.
Area of Science:
- Radiology
- Neuroimaging
Background:
- T2 FLAIR MRI sequences are crucial for detecting brain lesions.
- Artifacts in T2 FLAIR images can degrade diagnostic quality.
- Higher magnetic field strengths, like 3 Tesla (3T), may exacerbate these artifacts.
Purpose of the Study:
- To identify and evaluate the presence and frequency of T2 FLAIR artifacts.
- To assess artifacts on brain MRI studies specifically performed at 3T.
- To understand how common artifacts are and their potential to mimic pathology.
Main Methods:
- Retrospective review of 200 consecutive, unremarkable brain MRI studies.
- Analysis of axial T2 FLAIR images acquired at 3T.
- Evaluation for artifacts related to pulsatile cerebrospinal fluid (CSF) flow, magnetic susceptibility, and CSF signal nulling.
Main Results:
- T2 FLAIR images are prone to artifacts that can compromise image quality.
- Artifacts caused by pulsatile CSF flow, magnetic susceptibility, and inadequate CSF nulling were observed.
- These artifacts are particularly relevant at 3T, where they may be more severe or frequent.
Conclusions:
- T2 FLAIR artifacts are a significant consideration in 3T brain MRI.
- Awareness of these artifacts is essential for accurate interpretation and avoiding misdiagnosis.
- Increased artifact severity and frequency at 3T necessitate careful review of T2 FLAIR images.
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