Camptocormia in Chinese patients with Parkinson's disease

To investigate the frequency and clinical characteristics of camptocormia in Chinese PD patients, we included 705 patients with PD and studied the clinical features and prevalence of camptocormia. Forty-six (6.5%) patients presented with camptocormia at the time of evaluation. The mean disease duration of PD patients with camptocormia was significantly longer than that without camptocormia (P < 0.01). After adjusted for age and disease duration, compared with patients without camptocormia, PD patients with camptocormia presented with higher score of UPDRS part III (P < 0.01), higher H&Y stage (P < 0.01), higher score of Non-Motor Symptoms Scale (P < 0.01) and lower score of Mini-Mental Status Examination (P < 0.01). Binary logistic regression models indicated that camptocormia is associated with higher H&Y stage and UPDRS part III score. Camptocormia is not rare (6.5%) with the disease progression of PD in Chinese PD population and is associated with more advanced PD.