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Updated: May 4, 2026

Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
Toward effective probiotics for autism and other neurodevelopmental disorders
Jack A Gilbert1, Rosa Krajmalnik-Brown2, Dorota L Porazinska3
1Institute for Genomic and Systems Biology, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439, USA; Department of Ecology and Evolution, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637, USA.
Abstract:
Hsaio and colleagues link gut microbes to autism spectrum disorders (ASD) in a mouse model. They show that ASD symptoms are triggered by compositional and structural shifts of microbes and associated metabolites, but symptoms are relieved by a Bacteroides fragilis probiotic. Thus probiotics may provide therapeutic strategies for neurodevelopmental disorders.
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