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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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4,4'-Unsymmetrically substituted 3,3'-biphenyl alpha helical proteomimetics as potential coactivator binding

Patrick T Weiser1, Ching-Yi Chang2, Donald P McDonnell2

  • 1Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Ave., Boston, MA 02115, USA.

Bioorganic & Medicinal Chemistry
|December 24, 2013
PubMed

Keywords:
Co-activator binding inhibitionNuclear receptorProteomimetic

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