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Updated: May 4, 2026

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
Published on: April 6, 2022
Probiotics and liver disease
Vishal Sharma1, Shashank Garg2, Sourabh Aggarwal3
1Senior Research Associate at the Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. docvishalsharma@gmail.com.
Abstract:
Intestinal microbiota play an important role in health and disease. The gut-liver axis provides for an interaction between bacterial components like lipopolysaccharide and hepatic receptors (Toll-like receptors). Dysbiosis and altered intestinal permeability may modulate this interaction and therefore result in hepatic disorders or worsening of hepatic disorders. Administration of health-promoting microbial strains may help ameliorate these harmful interactions and hepatic disorders. This review focuses on changes in gut microbiota in the context of liver disease and possible roles of probiotics, prebiotics, and synbiotics in liver disease.
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